Dissolution Specifications and Ordering

Specifications and Ordering of spectrophotometers and accessories

Cecil Instruments policy is one of continuous development. We therefore reserve the right to change specifications without notice.

CE 3790 Tablet Dissolution Tester


Supplied complete; includes 7 graduated round bottom vessels, 7 plastic covers for vessels, perspex water bath mounted on a stainless steel base, polycarbonate bath cover, water heating coil, water circulation stirrer, drive head with pneumatically assisted lifting system. 7 PTFE paddles with coated shafts, connecting cable to PC, stainless steel sample tubing set, 2 sets silicon tube for peristaltic pump, set of tygon tubing for connecting to pump and from pump to spectrophotometer, immersion depth gauges.


CE 9260 Double Beam Spectrophotometer


190-800nm wavelength range, 1.8nm optical bandpass, dissolution sample compartment with flow tube port, 8 position cell changer, 8 cell holder, power cable, cable to PC and operators manual.


CE 7260 Double Beam Spectrophotometer


190-900nm wavelength range, 1.8nm optical bandpass, dissolution sample compartment with flow tube port, 8 position automatic cell changer, 8 cell holder, power cable, cable to PC and operators manual.


CE 3021D Single Beam Spectrophotometer


190-1100nm wavelength range, 1.8nm optical bandwidth, dissolution sample compartment and lid flow tube port, 8 position cell changer and cell holder, power cable, cable to PC and operators manual.


CE 3791 Peristaltic Pump


Eight channel variable speed peristaltic pump.


CE 3792 Dissolution Software


For dissolution system control and data processing.


ORDERING SYSTEMS


For convenience of ordering, Pharma Quest systems are offered which contain all the items required to assemble a working system and commence operation when flowcells and a PC with the appropriate specification are added.


System 1   With Double Beam Spectrophotometer.

CE 3790, CE 7260, CE 3791, CE 3792 and all items to complete the system. Requires flowcells and a PC.


System 2   With Single Beam Spectrophotometer.

CE 3790, CE 3021D, CE 3791, CE 3792 and all items to complete the system. Requires flowcells and a PC.


System 3   With Double Beam Spectrophotometer.

As System 1, with CE 9260 Super Aquarius spectrophotometer instead of the CE 7260 Aquarius spectrophotometer.


Alternative Dissolutions Systems


Systems may be based on the top of the range Super Aquarius double beam spectrophotometers CE 9260 and CE 9560. The CE 9560 is a variable resolution instrument with bandwidth selectable from 0.5nm to 4nm and the CE 9260 has a fixed bandwidth of 1.8nm. Both instruments have a photomultiplier detector and superb overall performance.


Both of these instruments use the same automatic 8-cell changer and holder that is used in the Aquarius CE 7260.


Flowcells - UV Grade Silica

1mm pathlength  

2mm pathlength  

5mm pathlength  

10mm pathlength  

 

Flowcells - Optical Glass

1mm pathlength  

2nm pathlength  

5mm pathlength  

10mm pathlength  

 

Spectrophotometer Spares

Deuterium lamp  

Tungsten halide lamp (in pairs)  

Fuse kit for CE7260  

Fuse kit for CE3021 D  

 

Vessels and Stirrers

Graduated 1 L clear glass vessel; certified  

Graduated 1 L brown glass vessel; certified  

PTFE paddles and coated stirrers, batch coded, set  

Stainless steel paddles and stirrers, batch coded, set  

Depth gauge for paddle stirrers  

Capsule sinker set, stainless steel  

Spindle with basket set; 10 grade mesh stainless steel  

Spindle with basket set; 40 grade mesh stainless steel  

Spindle with basket set; 100 grade mesh stainless steel  

Mesh disk set, 35mm diameter (USP/5)  

Mesh disk set, 85mm diameter (USP/5)  

Manual sampling syringe system  

Plastic cover for vessels  

Cover insert for water circulator position 8  

Stirrer shaft plastic adjustment screw  

 

Tubing and Filters

Silicone tube kit for pump  

Tygon tube installation kit  

Sintered filters - 10 micron (50 pcs)  

Stainless steel sampling tubes and connectors set  

 

Calibration

Stirrer wobble gauge, mounted  

Opto-electronic tachometer  

Digital thermometer and sensor; calibrated  



202 07 80

202 07 81

202 07 82

202 07 83

 

 

303 07 80

303 07 81

303 07 82

303 07 83

 

 

2202 01 42

2303 01 40

9070 27 00

2020 27 00

 

 

3790 01 01

3790 01 02

3790 02 01

3790 02 02

3790 02 03

3790 02 04

3790 03 01

3790 03 02

3790 03 03

3790 04 01

3790 04 02

3790 04 03

3790 04 04

3790 04 05

3790 04 06

 

 

3790 05 01

3790 05 02

3790 05 03

3790 05 04

 

 

3790 06 01

3790 06 02

3790 06 03

Dissolution Tools

A full range of tools is available for USP methods 1, 2 and 6. These include baskets in stainless steel, or gold plated, and paddles in stainless steel, or Telfon coated. Rotating cylinders are available, and devices for Transdermal studies of gels, suspensions and ointments.

Capsule Sinkers

These devices, ideal for formulations which will not sink under gravity, are made from stainless steel with snap tight closures and conform to Japanese Pharmacopoeia Specifications.

Wobble Tester

This tester, consisting of a spindle mounted dial gauge, enables any rotational wobble of the dissolution tool in its vessel to be measured and adjustments to be made to give less than ±0.2mm wobble.

Dissolution Baskets

Dissolution baskets are available in a range of mesh sizes to meet most requirements. Mesh sizes of 10, 40 and 100 mesh grades are available in standard form or gold plated.



Depth Gauges

These devices allow rapid and accurate setting of the stirring tool depth, and also vessel centring with a centring option. The devices simply snap onto paddle or basket tools.

Mesh Discs

For paddle over disc methods, (USP method 5), two sizes of mesh disc are available, 35 and 85mm diameter, which fit directly into standard dissolution vessels.

Dissolution Vessels

Graduated dissolution vessels, in clear glass, are available in standard or certified form. Vessels are numbered and specifications are to the USP standard. UV resistant amber glass vessels are also available.

Manual Sampling

A syringe system is available for simple and effective manual sampling from dissolution vessels and can be supplied with either a 5, or 10 micron filter.






CE 3791 Peristaltic Pump

The CE 3791 is a multi-cartridge design with good flow accuracy. Each of the eight channels may be individually released, or adjusted for roller operating pressure.


The images shown here are of the pump with flow tubes and the pump with one of the cartridges in the released position.